The effects of this medicine can be observed within 1 to 2 hours of administration. Consumer Information Use and Disclaimer However, many people have no side effects or only have minor side effects. See detailed T&C here. Ion Exchange Resin . Call your doctor right away if you have black, tarry, or bloody stools; constipation; stomach pain; swelling of the stomach; or throwing up blood or throw up that looks like coffee grounds. We investigated the long-term efficacy of oral CPS for treating mild hyperkalemia on an outpatient basis. that could elevate the blood calcium levels. © 2021 UpToDate, Inc. and its affiliates and/or licensors. Calcium Carbonate; Simethicone: (Major) Simultaneous oral administration of cation-donating antacids or laxatives may reduce the potassium exchange capability of sodium polystyrene sulfonate. Interaction with alcohol is unknown. Characteristic eosinophilic non-polarisable ⦠Legal Category: Product subject to medical prescription which may be renewed (B) ... Administer Calcium Resonium at least 3 hours before or 3 hours after other oral medications. This medicine is not recommended for use in patients with high levels of calcium in the blood (hypercalcemia) since it will worsen the patient's condition. If your child is a newborn. Most people who had these problems were also taking sorbitol. Polystyrene sulfonates are polymers derived from polystyrene but containing sulfonate functional groups. Sodium polystyrene sulfonate works by helping your body get rid of extra potassium. This medicine is not recommended for use in pregnant women unless absolutely necessary. Calcium Polystyrene Sulfonate 5/6. Log in to print or send this list to your patient and save lists of resources you use frequently. TOXICITY AND POISON MANAGEMENT (ANTIDOTES) in 21.TOXICITY AND POISON MANAGEMENT (ANTIDOTES) CALCIUM POLYSTYRENE SULFONATE: ANTIDOTE: PK: A: None E: Feces (100%) Indications & Dose: HYPERKALEMIA PO Adult 15g TID/QID as a suspension in water/syrup /as a sweetened paste Child 1g/kg/day in divided doses, MD 500mg/kg/day in divided ⦠Action And Clinical Pharmacology: Calcium polystyrene sulfonate is a cation exchange resin prepared in the calcium phase. E Calcium Polystyrene Sulfonate KALIMATE POWDER lèÅPolystyrene 9â10 Polystyrene (102/105) , 100% (14/14) 11-15 11-13 4â15 : Calcium Polystyrene Sulfonate Polystyrene Sulfonate lg Calcium Polystyrene Sulfonate , 5% 2% MethylcelluloseZ,ŸãjJJÑ DigitalisÄ] Digoxin¥ 20 Polystyrene S03Cal/2 S03Cal/2 5g X 105õ 500g Your dose regimen is specifically determined based on the electrolyte levels in the blood. The chance of these problems may be raised if you have low blood volume, kidney disease, or if you have ever had bowel disease or surgery. Do not flush down a toilet or pour down a drain unless you are told to do so. Sodium polystyrene sulfonate is a cation-exchange resin taken orally that is used to reduce high levels of potassium in the blood (hyperkalemia).Sodium polystyrene sulfonate removes potassium by exchanging sodium ions for potassium ions in the intestine. 23 September 2020. ⦠Use of this medicine may cause abnormal levels of calcium and magnesium in the blood, which may cause severe adverse effects. The sodium content of Calcium Resonium is less than 1 mg/g. Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: Clinical and experimental support for the hypothesis. Read about company. We use cookies to ensure that we give you the best experience on our website, If you continue without changing your settings, we'll assume that you are happy to receive all cookies on the medicine.ie website. Be ready to tell or show what was taken, how much, and when it happened. TOXICITY AND POISON MANAGEMENT (ANTIDOTES) in 21.TOXICITY AND POISON MANAGEMENT (ANTIDOTES) CALCIUM POLYSTYRENE SULFONATE: ANTIDOTE: PK: A: None E: Feces (100%) Indications & Dose: HYPERKALEMIA PO Adult 15g TID/QID as a suspension in water/syrup /as a sweetened paste Child 1g/kg/day in divided doses, MD 500mg/kg/day in divided ⦠Synonyms : Calcium Polystyrene Sulfonate, Sodium Polystyrene Sulfonate. Lillemoe KD, Romolo JL, Hamilton SR, Pennington LR, Burdick JF, Williams GM. If you have an allergy to calcium polystyrene sulfonate or any other part of this drug. The oral form of this medicine should not be given to neonates. Take or use sodium polystyrene sulfonate at around the same time(s) every day. It is used as a potassium binder in acute and chronic kidney disease for people with hyperkalemia (abnormal high blood serum potassium levels). Keep all drugs in a safe place. It may be given by mouth or given rectally. Very bad bowel problems like bleeding, swelling, and tearing have happened with this drug. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. This drug prevents many other drugs taken by mouth from getting into the body. Manufacturers advise take other drugs at least 3 hours before or after calcium- or sodium-polystyrene sulfonate; a 6-hour separation should be considered in gastroparesis. Some drugs may have another patient information leaflet. Pubchem.ncbi.nlm.nih.gov. Sign up for MyMSK to send your questions and receive answers to your most pressing concerns. Do not give this drug to a newborn. RESONIUM CALCIUM (calcium polystyrene sulfonate) is a cation exchange resin prepared in the calcium phase. C: Colonic necrosis due to calcium polystyrene sulfonate (Kalimate) not suspended in sorbitol. Hyperkalemia is prevalent in end-stage renal disease patients, being involved in life-threatening arrhythmias. This medicine may bind with other orally administered medicines which could decrease their effect or cause side effects. [Internet]. In vivo, the actual amount of potassium bound will be less than this. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Information on this page was last updated on 27 Sep 2018. Biophar Lifesciences Private Limited - Offering Calcium Polystyrene Sulfonate Powder Sachets, For Clinics and Hospitals, Packaging Size: 5*15 at Rs 560/box in Panchkula, Haryana. Background Calcium polystyrene sulfonate (CPS) has long been used to treat hyperkalemia in patients with chronic kidney disease (CKD). Each gram of resin has a theoretical in vitro exchange capacity of about 1.3 to 2 millimoles (mmol) of potassium (K+). If you are on a low-salt diet (sodium polystyrene sulfonate powder has salt), talk with your doctor. Limited. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. The rectal form is the preferred dosage form for neonates. This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Polystyrene sulfonate is usually supplied in either the sodium or calcium form. Calcium Polystyrene Sulfonate 5/6. If you think there has been an overdose, call your poison control center or get medical care right away. Cation-containing antacids (for example magnesium hydroxide, calcium carbonate) can reduce the effect of polystyrene sulfonate and metabolic acidosis can develop. As of 3/3, vaccines are available to MSK patients age 18 and over who live in New York State and who were treated for cancer at MSK on or after 1/1/18. Close monitoring of heart rhythm is recommended in these patients. All rights reserved, Practo Technologies Pvt. Description: Calcium polystyrene sulfonate is an ion-exchange resin used for reducing blood levels of potassium. What Calcium Resonium is used for Calcium Resonium is a type of medicine used to help remove excessive amounts of potassium from the blood. Do not use potassium supplements, calcium supplements, or salt substitutes while you are taking sodium polystyrene sulfonate, unless your doctor has told you to. Sodium polystyrene sulfonate may decrease your absorption of other medications. By sending a cheque (or) DD (Demand Draft, drawn on VIVAN Life Sciences Pvt. This information should not be used to decide whether or not to take this medicine or any other medicine. Calcium Resonium contains calcium polystyrene sulfonate which contains calcium atoms. 2018 [cited 24 September 2018]. Administration of this medicine should be stopped if the serum potassium levels fall to 5 mmol/liter. Medsafe.govt.nz. By Online Payment, by Master, VISA (or) American Express card, through our payment gateway console, as per the details provided in PI (Proforma Invoice). Polystyrene sulfonate is usually supplied in either the sodium or calcium form. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information is not specific medical advice and does not replace information you receive from the healthcare provider. Throw away unused or expired drugs. It is used for the treatment of hyperkalemia (high potassium levels) associated with kidney conditions such as anuria, severe oliguria, chronic kidney disease, etc. Calcium Resonium contains 99.93% calcium polystyrene sulfonate ground and flavoured to a vanilla odour and sweet taste. This includes your doctors, nurses, pharmacists, and dentists. Call your doctor for medical advice about side effects. Log in to print or send this list to your patient and save lists of resources you use frequently. It is used as a potassium binder in acute and chronic kidney disease for people with hyperkalemia (abnormal high blood serum potassium levels). Do not stop the use of this medicine without consulting your doctor. If you have slow stomach clearing (gastroparesis), talk with your doctor about when to take other drugs by mouth with this drug. If you are taking any of these drugs: Sorbitol or a laxative that has magnesium in it. You will need to talk about any risks to your baby. Calcium Carbonate: (Major) Simultaneous oral administration of cation-donating antacids or laxatives may reduce the potassium exchange capability of sodium polystyrene sulfonate. If you use this drug on a regular basis, use a missed dose as soon as you think about it. Background: Although polystyrene sulfonate (PS) is commonly used for the treatment of hyperkalemia, direct comparison of effects between calcium and sodium PS (CPS and SPS) on mineral and bone metabolism has not yet been studied. You should check all the possible interactions with your doctor before starting any medicine. It is used as a potassium binder in acute and chronic kidney disease for people with hyperkalaemia (abnormal high blood serum potassium levels). However, its efficacy and safety profile have not been systematically explored. 21A. It is used to treat high potassium levels. Sodium polystyrene sulfonate (SPS), a current treatment, binds potassium within the gastrointestinal tract to reduce potassium absorption. Read all information given to you. This medicine should be used with extreme caution in patients suffering from sarcoidosis due to the increased risk of elevated blood calcium levels and associated severe adverse effects. Available from: [Internet]. Calcium Resonium does not enter the If you're a patient at MSK and you need to reach a provider after 5:00, All rights owned and reserved by Memorial Sloan Kettering Cancer Center, © 2021 Memorial Sloan Kettering Cancer Center, Gerstner Sloan Kettering Graduate School of Biomedical Sciences. It can also be mixed with other drink or food like jam or honey. Rev Esp Enferm Dig. If you take other drugs by mouth, take them at least 3 hours before or 3 hours after this drug. 2 Qualitative and Quantitative Composition. Tell your doctor about the allergy and what signs you had. RESONIUM CALCIUM. Methods We performed a retrospective analysis of ambulatory ⦠Calcium Resonium does not enter the Calcium polystyrene sulfonate - chemical information, properties, structures, articles, patents and more chemical data. Medicines.org.uk. If your potassium level is normal or low. Take/administer this medicine exactly as prescribed by the doctor. Calcium Polystyrene Sulfonate - Last updated on February 3, 2021 All rights owned and reserved by Memorial Sloan Kettering Cancer Center. Ion-exchange resins, sodium or calcium polystyrene sulfonate, are commonly used medications for management of hyperkalaemia. The objective was to compare the efficacy and safety of two different cation exchange resins (CPS and SPS) in patients of CKD with hyperkalemia. Patients should be monitored for all applicable electrolyte disturbances during therapy with this medicine. It is a potassium-binding ion-exchange resin that can be administered orally (25 grams in 20% sorbitol) or rectally (50 grams in 20% sorbitol). The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Each gram of resin has a theoretical in vitroexchange capacity of about 1.3 to 2 millimoles (mmol) of potassium (K+). If you are on a low-salt diet (sodium polystyrene sulfonate powder has salt), talk with your doctor. This is not an exhaustive list of possible drug interactions. Examples of cation-donating antacids and laxatives include aluminum hydroxide, calcium carbonate, magnesium carbonate, magnesium citrate, and magnesium hydroxide. Manufacturers advise take other drugs at least 3 hours before or after calcium- or sodium-polystyrene sulfonate; a 6-hour separation should be considered in gastroparesis. Do not take in larger or smaller quantities than recommended. You should consult your doctor about all the possible interactions of the drugs youâre taking. This is only a brief summary of general information about this medicine. However, the drug can be associated with serious bowel injury. Compared with SPS, CPS may have a higher potassium-selectivity at cation exchange 20). This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. Hence, it is advised that you report all your current medicines, including any herbs and supplements, to the doctor before beginning treatment with this medicine. If you have any of these health problems: Cancer that has spread to other parts of the body, multiple myeloma, overactive parathyroid gland, or sarcoidosis. If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. Published 17 April 2011, updated 10 August 2020. Manufacturer of Bulk Actives Drugs - Cholestyramine, Calcium Polystyrene Sulfonate , JP, Cholestyrami-ne Resin , USP and Calcium Polystyrene Sulfonate , BP offered by Phaex Polymers Private Limited, Badlapur, Maharashtra. 21A. If your symptoms or health problems do not get better or if they become worse, call your doctor. Replacement with a suitable alternative should be considered based on the patient's clinical condition. For more info, and if you live in NJ: Read more. Create a custom communication board for patients who are not able to use their voice. Follow all instructions closely. Calcium Resonium contains calcium polystyrene sulfonate which contains calcium atoms. By sending a cheque (or) DD (Demand Draft, drawn on VIVAN Life Sciences Pvt. Sodium polystyrene sulfonate is usually taken or used one to four times a day. It is also not recommended for use in patients suffering from conditions such as hyperparathyroidism, multiple myeloma, sarcoidosis, metastatic carcinoma, etc. Tell all of your health care providers that you take sodium polystyrene sulfonate powder. You will need to talk about the benefits and risks of using this drug while you are pregnant. Monitor calcium and magnesium in patients receiving sodium polystyrene sulfonate. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. If you are not able to do this, talk with your doctor. Polystyrene sulfonate is usually supplied in the sodium and calcium form. Ion-exchange resins, sodium or calcium polystyrene sulfonate, are commonly used medications for management of hyperkalaemia. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Do not start, stop, or change the dose of any drug without checking with your doctor. Calcium Polystyrene Sulfonate is used for reducing blood levels of potassium. This medicine is not recommended for use in patients with low blood potassium levels (less than 5 mmol/L) since it will worsen the patient's condition. This is not a list of all drugs or health problems that interact with this drug. It however is unclear if it works and there is concern about possible side effects when it is mixed with sorbitol. Consult top doctors online and get an answer now, Book an appointment with the top doctors near you, Copyright © 2017, Practo. Be ready to tell or show what was taken, how much, and when it happened. Antacids or laxatives can make sodium polystyrene sulfonate less effective, or cause serious side effects. Talk with the doctor. Report any unusual symptoms to the doctor immediately. Each gram of resin has a theoretical in vitro exchange capacity of ⦠High molecular weight insoluble polymers which contain functional anionic groups that are capable of undergoing exchange reactions with cations. Excipients with known effect. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine. Log in to create and save frequently used communication boards. No habit-forming tendencies were reported. 2013 Apr;105:232-234. Check with your pharmacist if you have questions about the best way to throw out drugs. [3] Educational Resources. This medicine may interact with many other medicines and may cause severe adverse effects. It is advisable to consult your doctor before consumption. Manufacturers advise take other drugs at least 3 hours before or after calcium- or sodium-polystyrene sulfonate; a 6-hour separation should be considered in gastroparesis. Signs of low potassium levels like muscle pain or weakness, muscle cramps, or a heartbeat that does not feel normal. You may report side effects to the FDA at 1-800-332-1088. Calcium polystyrene sulfonate (Calcium Resonium®) â Adult Page 2 of 2 Adult Medication Monograph Monitoring Initially, both oral and rectal routes may be used to reduce potassium concentration more rapidly Monitor potassium concentration during treatment and adjust dose if necessary. We report a case of a renal transplant recipient who developed duodenal ulcer perforation secondary to the use of calcium polystyrene sulfonate. Sodium polystyrene sulphonate (SPS) and calcium polystyrene sulphonate (CPS) are currently used for hyperklemia of CKD all over the world. 346361003 Articles. Use this drug as ordered by your doctor. This includes your doctors, nurses, pharmacists, and dentists. If it is almost time for the next scheduled dose, then the missed dose can be skipped. All drugs interact differently for person to person. Calcium polystyrene sulfonate. This medicine is not recommended for use in patients suffering from chronic constipation since it may worsen the patient's condition and cause severe adverse effects. This medicine is not recommended for use in patients with an obstructive disease of the gastrointestinal tract due to the increased risk of worsening of the patient's condition. Products.sanofi.ca. Calcium polystyrene sulfonate Haematological disorders Safety in Breastfeeding. Available from: [Internet]. Anmol Chemicals is the pioneer manufacturers of Calcium Polystyrene Sulfonate, Pharmaceutical Excipients Fragrance & Flavor chemicals in India.We supply Halal and Kosher Calcium Polystyrene Sulfonate made in an ISO9001, ISO22000 (FSSC22000) and cGMP certified facility. Calcium content is about 8% w/w (1.6-2.4 mmol/g). Polystyrene sulfonate is used to treat high levels of potassium in the blood, also called hyperkalemia. Sometimes, this has been deadly. Hyperkalemia is a lifeâthreatening emergency in maintenance hemodialysis (MHD) patients. Signs of high calcium levels like weakness, confusion, feeling tired, headache, upset stomach and throwing up, constipation, or bone pain. It is used as a potassium binder in acute and chronic kidney disease for people with hyperkalemia (abnormal high blood serum potassium levels). This medicine is not recommended for use in patients with a known allergy to calcium polystyrene sulfonate, any polystyrene sulfonate resins, or any other inactive ingredients present in the formulation. We report a case of a renal transplant recipient who developed duodenal ulcer perforation secondary to the use of calcium polystyrene sulfonate. Store in a dry place. Weâve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. 2013 Apr;105:232-234. Use with care in children. Rev Esp Enferm Dig. What are some things I need to know or do while I take Sodium Polystyrene Sulfonate Powder? Crosslinked materials (called resins) do not dissolve in water and typically appear amber in color. Sodium polystyrene sulfonate comes as a suspension and as an oral powder for suspension to take by mouth. Tell all of your health care providers that you take sodium polystyrene sulfonate powder. In a randomized and crossover design, 20 pre ⦠Cation-containing antacids (for example magnesium hydroxide, calcium carbonate) can reduce the effect of polystyrene sulfonate and metabolic acidosis can develop. This clinical trial investigated the efficacy and safety of calciumâpolystyrene sulfonate (CaâPS) in MHD patients with interdialytic hyperkalemia.
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